There’s drugnerd whispers on the internet that DXM (microdosed) can block or attenuate the development of tolerance to various ligands, particularly amphetamine.

Any DrugNerdz here who can explain the valudity of this conjecture or expand on it in any helpful way

  • cheese_greater@lemmy.worldOP
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    1 year ago

    I wouldn’t say its any absolute, it can play a role in mentally resetting you at the hyperdosage level. Almost like a “hard reset” like when you turn off your device or whatever

    Personally, I agree that it can be very dangerous as well both acutely and over chronic usage. We don’t know much about potential kidney issues like with ketamine or if there’s any other nasty health risks like Olney’s lesions etc.